INTRODUCTION The development of orally administered small molecules is becoming more challenging as an increasing number of molecules in pipelines have poor…
Why has solubility become a challenging aspect? The effectiveness of orally administered medicines hinges on the drug’s ability to dissolve in the gastrointestinal tract and promptly…
Employing information regarding an active pharmaceutical ingredient’s physicochemical characteristics obtained from pre-formulation and formulation investigations enhances the probability of achieving success in…
INTRODUCTION The development of new chemical entities (NCEs) has shifted in recent years toward smaller drug developers, creating a more varied market…
To ensure the physical and chemical stability of Lipid-Based Formulations (LBFs), it is essential to find a delicate balance between the formulation…
DRUG DEVELOPMENT AND FORMULATION IS SCIENCE. DOSE DESIGN TO CREATE SUCCESSFUL TREATMENTS IS ART. Developing successful treatments that meet the needs of…