This appraisal will intensively scrutinize the critical variables that must be meticulously considered and the formidable challenges that are invariably encountered during…
INTRODUCTION The development of new chemical entities (NCEs) has shifted in recent years toward smaller drug developers, creating a more varied market…
Why has solubility become a challenging aspect? The effectiveness of orally administered medicines hinges on the drug’s ability to dissolve in the gastrointestinal tract and promptly…
Introduction Overcoming drug development challenges requires a science-driven approach enhanced by data-driven decision-making and working with the right contract development and manufacturing…
INTRODUCTION The development of orally administered small molecules is becoming more challenging as an increasing number of molecules in pipelines have poor…
Utilizing strategies that conserve active pharmaceutical ingredient (API) quantities and pinpointing scalable formulation technologies suitable for boosting drug solubility and augmenting oral…
Employing information regarding an active pharmaceutical ingredient’s physicochemical characteristics obtained from pre-formulation and formulation investigations enhances the probability of achieving success in…
Orphan drugs encounter challenges that extend from their initial discovery to eventual launch, primarily due to the restricted patient numbers and niche…